To diagnose hypophosphatasia (HPP)

To diagnose hypophosphatasia (HPP)

Connect perplexing symptoms with persistently low alkaline phosphatase (ALP)1-3

Persistently low ALP can differentiate HPP from other metabolic disorders with overlapping symptoms.

Patient image

Patient image is hypothetical.

In these patients, check ALP levels on their comprehensive metabolic panel1

Make the connection between low ALP and HPP.
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Hear from HCPs with Experience

Lynn Kohlmeier, MD - Adult Endocrinologist

Lynn Kohlmeier, MD(1:41)

Adult Endocrinologist

Eric Rush, MD - Clinical Geneticist

Eric Rush, MD(4:22)

Clinical Geneticist


References: 1. Bianchi ML, et al. Osteoporos Int. 2020;31(8):1445-1460. doi: 10.1007/s00198-020-05345-9. 2. Mornet E. Hypophosphatasia. In: Adam MP, Ardinger HH, Pagon RA, et al, eds. GeneReviews®. University of Washington; 2007. Accessed November 4, 2021. https://www.ncbi.nlm.nih.gov/books/NBK1150/ 3. McKiernan FE, et al. J Bone and Miner Res. 2014;29(7):1651-1660. doi: 10.1002/jbmr.2178 4. Rockman-Greenberg C. Pediatr Endocrinol Rev. 2013;10(suppl 2):380-388.